Urinary Phenols in Neuroblastoma

A Quantitative Method of Determining Urinary Phenols.

‘IT0STUDY PROTEIN METABOLISM with special reference to tyrosine as well as to study the deranged metabolism of aromatic compounds in phenylketonuria and similar disorders, quantitative determination of urinary phenols is desirable. Volterra (1) measured three phenolic fractions in the urine by distillation. Phenols have been measured quantitatively after ethyl acetate extraction by Bray and Tho...

Bone Involvement in Neuroblastoma

Urinary cystathionine, catecholamine, and metabolites in patients with neuroblastoma.

Urinary excretions of cystathionine, catecholamines, and vanillymandelic acidwere compared in 27 patients with neuroblastoma and in nine other patients with non-neurogenic tumors. Eleven of the 27 patientswere withoutclinical evidence of activeneuroblastomaatthe time ofthe study and excretedno or relatively small amounts of urinarycystathionine. Thirteenof the remaining 16 patients with progres...

Molecular Markers in Neuroblastoma

Neuroblastoma, one of the common malignant childhood tumors, arises from neuroblast cells derived from theneural crest and destined for the adrenal medulla and the sympathetic nervous system and shows remarkable biologicalheterogeneity, resulting in favorable or unfavorable outcomes. Some tumors make rapid progress with a fataloutcome. In other instances, the tumors regress spontaneously in inf...

Prenatal Exposure to Environmental Phenols: Concentrations in Amniotic Fluid and Variability in Urinary Concentrations during Pregnancy

BACKGROUND Maternal urinary biomarkers are often used to assess fetal exposure to phenols and their precursors. Their effectiveness as a measure of exposure in epidemiological studies depends on their variability during pregnancy and their ability to accurately predict fetal exposure. OBJECTIVES We assessed the relationship between urinary and amniotic fluid concentrations of nine environment...